https://anthbapt.github.io/tags/mathematical-biology/Mathematical BiologyHugoBlox Kit (https://hugoblox.com)en-usFri, 01 Nov 2024 00:00:00 +0000https://anthbapt.github.io/media/icon_hu_da05098ef60dc2e7.pnghttps://anthbapt.github.io/tags/mathematical-biology/https://anthbapt.github.io/projects/graph-rwr/Fri, 01 Nov 2024 00:00:00 +0000https://anthbapt.github.io/projects/graph-rwr/<p>This project explores the use of random walk with restart (RWR) on tissue neighbourhood graphs to define cell–cell communication in the spatial transcriptomics context.</p> <p>Key contributions:</p> <ul> <li><strong>Synthetic data generator</strong>: Simulation of ligand-receptor signalling for benchmarking</li> <li><strong>Practical methods</strong>: Scalable RWR-based inference of communication patterns in spatial transcriptomics data</li> </ul>